Jack, Samantha and Danny search for the mercenary who escaped after killing the terrorist in Martin and Danny's custody and leaving the bullet-riddled Martin at death's door.

The team investigates whether a 15-year-old whiz kid is missing of his own accord in order to execute his elaborate plan to bomb his high school.

The team's newest member, F.B.I. rookie Elena Delgado, formerly of the N.Y.P.D., encounters a learning curve as she attempts to help search for a missing young prostitute.

Jack fears that he may have elicited a wrongful murder confession during an intense interrogation seven years ago when new evidence suggests that the convicted professor's missing former student-lover may actually be alive.

The team searches for a 25-year-old Korean-American who vanishes after a fight with her new boyfriend during her night shift at her parents' deli.

Jack and Danny head to Mexico to find a wealthy American vacationer who was abducted at gunpoint in front of his wife.

The team's search for a man who let his marriage and career slip away following his teenage daughter's death leads them to also look for a young girl featured in porn photos found in the missing man's home.

This unique episode told from the point of view of the missing person's parents features the emotional rollercoaster of the mother and father of a missing 15-year-old boy as the team does its best to find him.

The team investigates whether the industrial espionage case that Max and his partner, Jimmy, were working on is connected to Jimmy's murder and if Max is now a victim of Jimmy's killer. They soon learn that, as a safety precaution, Max attempted to pull Jimmy from the case, but that Jimmy threatened to tell Anne a secret about Max if Max removed him. Now, the team has to consider Anne as a possible suspect in her husband's disappearance.

As a favor to a friend who works at a mental ward, Sam helps a woman who was brought in suffering from amnesia. Meanwhile, Jack learns that his dad is experiencing kidney failure, and tries to convince him that he should have an operation.

The team investigates when a young paramedic disappears following a gang-related incident and question the paramedic’s own gang affiliations.

The team investigates the fiancA© of a missing therapist after learning that she may have been cheating on him.

The team investigates when a student believed to be involved with a student disappears after a confrontation with a man at the gym.

A former marine, who had served five years for a rape conviction in Tokyo, disappears shortly after appearing in a police lineup for a local rape and being released when he isn't picked.

The team investigates after a woman disappears shortly after having a confrontation at a Manhattan art gallery.

The team searches for five-year-old Ethan Heller after he is kidnapped in front of his home.

The team joins the hunt for a columnist who stopped leaving her apartment after a series of panic attacks.

The team searches for a missing bicycle messenger and soon learn that he is a 15-year-old boy who has been trying to keep his family together since his mother disappeared the year before.

The team investigates after a pregnant woman with HIV disappears.

The team searches for a young blue blood who went missing from the inner city shelter for indigent women where he volunteered as part of his sentence for drug possession. As the agents investigate whether Breck Mulligan was victimized by one of the shelter’s resident’s abusive husbands, pimps or dealers, they also ponder if Breck, a repeat drug offender, fell back into that dangerous world. Breck’s powerful father counters that his reformed son was likely kidnapped in the shelter’s dicey neighborhood by someone seeking a hefty ransom. After learning that Breck’s father cut him off financially following his arrest, the agents also wonder what Breck did to obtain thousands of dollars from anonymous donors to keep the shelter open.

The team attempts to locate a 15-year-old Olympic-hopeful figure skater who was last seen at the local ice rink as she practiced for the next day's competition. Suspects include the ice rink's manager, who used a different surname to hide the fact that he had served time for raping a teen-aged girl, the anonymous person who left a decapitated rat inside Kelly's locker, and the 40-something man with whom she had an emotional conversation in a parking lot two weeks ago. Meanwhile, though Jack is excited to introduce Anne to his younger daughter, Kate, Anne is anxious about how Kate will respond to meeting her.

As the team searches for a recent widower and his two teen-aged kids, they attempt to determine who is responsible for the gunfire which left the missing family's living room splattered with blood. The Jordano family was last seen through their partially opened front door by neighbors who report that the visibly nervous Ted declined to let his son, Dylan, join them on their scheduled outing to a baseball game. After learning that Ted, a new gun owner, remains despondent over his wife's death and his mounting debt, the team considers that it may be he who is responsible for the bloodshed and disappearance. Under investigation as well are a loan shark who has been hounding Ted and his daughter's delinquent boyfriend. The potential suspects and scenarios for this case seem endless to the team members who realize that with three missing people there are three times as many reasons for them to have vanished.

When a white teen-aged girl and an African-American teen-aged boy coincidentally vanish on the same night, Jack attempts to counteract Vivian's prediction that the media and FBI will focus on the white girl's case. Despite Jack's attempts to generate press on both cases, Emily Grant's disappearance garners all of the media attention and, as a result, gets a steady stream of leads. As Vivian anticipates, Van Doran orders Jack to allocate more resources to follow up on the leads on Emily's case, which means diverting FBI attention away from the Darnell Williams investigation. Well aware of the turn of events, Darnell's mother, Audrey pointedly asks Jack who is running the investigations: the FBI or the media?

While investigating the disappearance of a young female former assistant district attorney, Jack and the rest of the team are blindsided when the woman's ex-boyfriend suddenly opens fire on the FBI offices. When Alan Davis, the former boyfriend of the missing Jennifer Nichols, realizes that he's a suspect in her disappearance, he suddenly pummels Jack, grabs Jack's gun and bolts out of the FBI building while firing a hail of bullets. Before and after the shooting, Jack and the team delve into Alan's background and possible motives while also looking into the relevance of Jennifer's mysterious visit to a prisoner the night before she vanished.