The team searches for a girl who recently became blind and her instructor who are camping out in the woods.

The team searches for a woman who went missing while changing the tire on her car.

The team searches for a man who believes he was abducted by aliens as a child. He disappears from his apartment after ranting that they are out to get him.

The team searches for a child who disappears at the same time her nanny. The team must determine if the nanny is a suspect or a victim.

The team searches for a winner of TV make-over show. She disappears in the middle of a publicity event that surrounds her.

The team searches for a young mother who disappeared after requesting the babysitter watch her daughter at the last minute.

Samantha goes undercover in the continued search to the young mother.

When a homeless woman disappears from a shelter, the team is forced to re-examine the case of twin brothers Greg and Rick Knowles. Five months earlier (in Doppelganger), Greg Knowles had confessed to a series of brutal murders, but the team was always convinced that it was Rick who had actually performed the killings. When Greg is released from jail and exonerated of the crimes, the team has to work against the clock to prove that Rick is the guilty party and to save one twin from the other.

The team searches for an old man whose disappearance could lead the mistrial.

Jack gives his deposition to his wife’s divorce attorney in the battle to have custody of his children.

Tara Patterson disappears from a bus stop on her way to an S.A.T. prep course, and the team is called in to investigate the disappearance of the 4.0 student. While investigating, the team soon finds out that Tara is in deeper then they think when they start learning about smart drugs and married men with secrets.

When Mac, a prisoner only two weeks from parole, disappears during a fight in the yard along with another prisoner, his sister contacts the FBI for help. No one can figure out why a member of the Aryan gang would escape with a black prisoner. While Martin and Viv talk to the other prisoners and Jack tries to wade his way through the sister’s lies and half-truths where her brother is concerned, Danny focuses on a new prisoner who Mac had been protecting.

When Ian Norville disappears on a field trip to a museum in Manhattan, the team gets involved, but it isn’t long before Jack turns his suspicion to his father, Daniel, who soon admits that he didn’t take the necessary precautions with his son, who happens to be autistic.

After postal worker Rosie Diaz goes missing during what seemed to be a regular workday, the team initially connects her disappearance to her cargo, which include $12,000 worth of the game Demon Storm, which all the kids were after. But when the team gets in touch with child protective services, they learn that Rosie recently had her foster children taken away after an anonymous abuse call. A search of her home uncovers a DVD containing child pornography, and the team starts to look at the case from another angle. Danny comments on Martin and Sam’s obvious closeness, and wonders why they’re keeping it quiet. Vivian learns that she has hypertrophic cardiomyopathy and will require surgery.

When a spoiled heiress in her early twenties is kidnapped, the team has to work against the clock to save Chelsea, who is being featured on a website giving fans the option to choose whether she lives or dies. As they continue to investigate her disappearance, the team learns that Chelsea had finally been starting to grow up, but she may not have time to enjoy her new life.

Martin is swamped with guilt after a young boy is kidnapped shortly after he jogs by. The team tries to reassure Martin that his presence was a help rather than a hindrance as they search for the kidnapped child, but Sam’s continued reluctance to admit to their relationship partnered with Martin’s jealousy of her relationship with Jack only cause more problems...

Lance Hamilton is a successful real estate agent in his early thirties who disappears one day after showing a house. When the team gets involved, they soon realise that Lance had more than one dealing with a local hood, Jimmy ’The Tooth’ Fusco, and begin to suspect that Lance may not have been the good guy everyone thought he was. After tracking down the woman Lance had recently been spotted kissing in his office, the team needs to revise their opinion, knowing now that Lance is one of the good guys, but wondering if he’s died for his beliefs.

When Stephanie Healy doesn’t show up for choir practice, the team heads in to investigate and soon learns Stephanie had recently had a fight with her boyfriend. While speaking with Eddie, the team is shocked to learn that Stephanie used to be Stephen Patrick Healy. Convinced that the truth to what is happening in Stephanie’s present lies in her past, the team investigates who Stephen was. Vivian has trouble hiding her worsening problems from the team, and is upset that Martin has been talking to Sam about his suspicions.

After a young woman named Agnes Deschamps goes missing, the team takes a look into her disappearance and learns that the young woman was believed to be a psychic. Sam has trouble accepting that one of their witnesses purports to be a psychic, although she is thrown when the woman correctly points out her problems with Martin. Jack, Martin and Danny pick up the extra hours with Vivian out awaiting heart surgery and together the team manages to track the young woman down after a supermarket parking lot kidnapping yeilds an unlikely clue.

Seven years ago, a thirteen-year-old girl named Amber Bryce went missing, and suspicion fell on her boyfriend, then-seventeen-year-old Curtis Horne. When Daisy Thorpe, who had become obsessed with getting justice for Amber’s death, also ends up missing, the team is called in to investigate. While Martin and Danny work from the office, Sam and Jack work in the field, starting their investigation with the local cleric, Amber’s father, and trying to find out why Curtis Horne has stayed in town all these years. While Vivian is home having troubles with Reggie, Martin makes a decision about his relationship with Sam.

Danny is skeptical when the pregnant girlfriend of his missing estranged brother, Rafael "Rafi" Alvarez, and mother of their 9-year-old son, tells him that Rafi has transformed himself into a responsible family man, who recently obtained a loan to open his own body shop. But Danny’s investigation uncovers that Rafi has been seen with a convicted car thief, and the large sum of cash he’d been flaunting for his purchase of a body shop didn’t come from the bank. Though Jack makes the point that Rafi may have legitimate explanations for the suspicious circumstances, Danny braces himself for the very real possibility that his brother may have put himself in harm’s way.

The team launch an inquiry into the disappearance of a 71-year-old insurance investigator, who was last seen getting into a car with two unknown men. They learn he had been trying to make amends with his ex-wife and help his daughter sort her life out - but the case throws up a few unusual twists.

Jack and the team begin a baffling investigation into a woman’s disappearance. They discover an NYPD detective was making enquiries about her at around the time she went missing - but the policeman turns out to be an imposter. Further evidence suggests she was involved in an identity theft scam - and might even be connected with terrorist activity. Meanwhile, Vivian undergoes open heart surgery.