The Missing Persons Squad of the FBI searches for a 28-year-old marketing executive who disappears. The woman is last seen by her doorman and the security tape shows her leaving alone by the back door.

The team searches for a boy who disappeared on his way to the stadium for a New York Yankees game on his 11th birthday. The boy became separated from his father in the subway station.

A man who is out shopping with his wife realizes that he needs to go back into the store to retrieve his credit card. After the husband walks away, his wife’s car speeds off, leaving an injured bystander. Witnesses say an unknown assailant forced the frightened wife into the car and drove away.

A model disappears leaving a half-packed suitcase on her bed in her apartment. The problem is nobody knows what she looks like because she changes her appearance according to the modeling or acting job that she is trying to get at the time.

The team searches for a 17-year old student who disappears from his boarding school. The boy was last seen with the headmaster of the school.

The team searches for a New York businessman who disappears after checking in for a flight home.

The team searches for the daughter of an assistant district attorney who disappeared from a park. The child was playing with another child while under the care of her nanny.

The team searches for a teenager who went missing in a bad neighborhood after an encounter with a bully.

The team searches for a medical intern of Saudi Arabian decent. He disappears after a refusal to write a letter of recommendation by his boss and a turned down marriage proposal to his girlfriend.

The team searches for a man who left his home to open his business and take his daughter to school and neither are seen again.

Annie Miller disappears on her way to school. The group looks into her disappearance, with their suspects ranging from the local mayor, to Annie's godfather, all the way to a young man working for the father of her best friend. Twenty-four hours after Annie's disappearance, her best friend Siobhan Arintero also vanishes, leaving only a collection of videos to help find the two girls.

The team searches for a pregnant woman who disappears from the emergency room. The doctors didn, 't get a chance to tell her that she has an illness that put both her and her baby, 's life in jeopardy.

The team searches for a man who has been desperately searching for his son ever since he was kidnapped.

The team searches for a flight attendant who fails to appear for her flight.

A bride disappears at her own wedding and suspicions of kidnapping. Meanwhile, the team explores the relationship between the newlyweds, who lived together for a little while.

The team searches for a girl who disappeared from a mental hospital. The last person to see her was an employee who put her in isolation.

The team searches for a retired Army officer who disappears after a dinner given in his honor by the men he was in Vietnam with.

The team searches for a TV reporter who disappeared during the middle of an investigation. The last person she called was Jack.

They search for a young high-school teacher who disappeared after a night class in the Bronx, turning up contradictory information about the subject. They soon find out that he is having a relationship with a student at his school. Aired: 4-10-2003

The team searches for a boxer who disappears before a $500,000 fight. He is last seen by his trainer.

The team has to defend its methods in the suspect episode in order to keep the case from being thrown out of court. Also the Office of Professional Responsibility investigates the team.

In the aftershocks of Sept. 11, a man named Barry (who lost his wife that day and then his job soon after) lashes out at her former boss, an employment-agency owner. Blaming her for his wife’s death and his own failure to find a job, Barry kidnaps the woman for ransom.Then he demands the money be exchanged at a bookstore, but when the cash is delivered, Barry is provoked and takes the store’s patrons hostage. Among them is Samantha,and Jack’s affection for her complicates the negotiations.

The team tries to plot a strategy after they find out that Samantha has been shot and might be critically injured in a hostage crisis situation. Jack makes a deal with Barry so that Sam can get help: Jack goes in there and takes Sam's place.